Venereal granuloma- chronic slowly progressive infectious disease that is transmitted mainly through sexual contact, characterized by the development of extensive granulomatous ulcerations of the skin and subcutaneous tissue, mainly in the genital area and perineum. Frequency. Endemic tropical disease, common in New Guinea, India, the Caribbean, South Africa. In the United States and European countries do not register often. In the world, the incidence is 1.5% of the total incidence of venereal diseases. The prevailing age is 20-40 years. Etiology. The causative agent is Calymmatobacterium granulomatis (a polymorphic, gram-negative ovoid or bean-shaped microorganism, having the form of a cocci or short stick).
Length- 1-2 microns, width - 0.6-0.8 microns, forms a capsule. Infection occurs through sexual intercourse, more rarely - domestic. Risk factors
The clinical picture.Incubation period- from several days to 3 months. At the site of introduction of the pathogen (often in the area of the glans penis, labia) there is a nodule that undergoes purulent disintegration with the formation of a juicy, bright red color, soft to the touch ulcerated plane with a grainy bottom and uneven raised edges, almost painless during palpation. The ulcer slowly grows around the periphery, is sharply limited from the surrounding skin, an increasing mass of granulations appears at the bottom. Depending on the clinical course, ulcerative, verrucous, blooming, necrotic, sclerosing granulomas are distinguished. The reaction of the lymph nodes depends on the shape of the process. The general condition of the diseased is not often disturbed. The course of the disease is chronic.